In order to study the problem of vehicle bridge coupling vibration response to the relative motion of bridge structure at different support under the effect of accidental external strong excitation, a type of the close contact vehicle-bridge coupling dynamics model is presented. The separation variable method is performed to analyze the coupling equation and to discuss the dynamic response of the vehicle-bridge coupled system under the non-inertial reference view. With single span beam as an example, the beam body rotation velocity effect on vehicle-bridge dynamic responses of the coupled system is discussed. The researches demonstrated that in occasional strong external incentives (e.g. earthquake) caused the relative horizontal rotation of bridge structure, due to the rotation velocity is coupled with the displacement and velocity of the bridge structure, the angular velocity of rotation has an important influence on the vibration response of the bridge structure, applying the non-inertial reference frame to describe and analyze the vehicle-bridge coupled dynamic system would be more intuitive and convenient, when the bridge structure occur the horizontal rotation motion(relative to the ground) caused by the occasional strong external excitation.