[Purposes] This paper aims to reveal the effects of inherent anisotropy and deviatoric stress q on the mechanical properties of sand and deepen the understanding of soil dependence on stress direction. [Methods] Hollow cylinder specimens of sand with inherent anisotropy were prepared by using a new specimen preparation device. The hollow cylinder apparatus was used, and a series of undrained pure principal stress rotation tests were carried out under conditions of different bedding plane [α3] and q. [Findings] During the pure principal stress rotation, the critical rotation cycle of sand varies with the change of [α3] or q, and the maximum numerical difference can be 9 times. The accumulation rate of pore pressure in the early stage is also related with [α3] and q, but the stable pore pressure value in the middle stage is less affected by the two parameters. With the increase in [α3] and q, the accumulation rate of shear strain is accelerated, and the area of hysteresis loops and the dip angle also change. [Conclusions] The dynamic properties of sand, such as strain development patterns, pore pressure changes, and shear stress-shear strain relationship, are all closely related with the inherent anisotropy and q, and changes in q affect the relationship between the inherent anisotropy and the dynamic properties.