[Purposes] Hybrid fiber reinforced cement mortar was prepared using domestically produced PVA fibers, modified PP fibers, calcium carbonate whiskers, and tailings sand as a partial substitute to quartz sand, to study the mechanical properties of the mortar and to explore the optimum mixing amount of tailings sand. [Methods] The workability and mechanical properties of the mortar were tested by changing the dosage and gradation of tailings sand, and the micro-morphology was observed to determine the optimal dosage parameters of tailings sand. [Findings] When the optimum dosage of tailings sand is 50% and the gradation range is Ts-150, the mortar shows the optimal performances: When compared with the control sample, the fluidity decreased by 5.46% , and the 7 d and 28 d compressive strength increased by 22.07% and 16.86%, respectively; the 7 d and 28 d flexural strength increased by 31.36% and 24.42%, respectively; and the 7 d and 28 d cleavage tensile strength increased by 17.63% and 46.84%, respectively. 17.63% and 46.84% respectively. Scanning electron microscope test results show that the hydration products and tailing sand particles are well bonded in the cement mortar. [Conclusions] Results of this study indicate that it is feasible to produce hybrid fiber reinforced cement mortars with tailing sand as a replacement of quartz sand, which can lead to considerable economic and environmental benefits.