[Purposes] The design of cementitious materials utilizing solid waste to replace cement, which reduces energy and resource consumption and environmental pollution, as well as realizes the resource utilization of solid waste. Based on the reaction mechanism of alkali-activated binder and the action mechanism of their raw material components, this paper proposes a design method of all-solid-waste-based alkali-activated binders. [Methods]The CGF+P series cementitious materials comprising calcium carbide slag (CCR), ground granulated blast furnace slag (GGBS), fly ash (FA), and phosphogypsum (PG) are designed, and the design method is verified by using macro and micro tests of paste. [Findings] The alkali activator and pozzolanic materials with highly activity have a significant effect on the setting time of paste, the higher its content, the shorter the initial and final setting time; The strength of paste is governed by the relative content of alkali activator and pozzolanic materials, the higher the content of pozzolanic materials with highly activity the higher the early strength, and vice versa. [Conclusions] The design method of all-solid-waste-based alkali-activated binders includes component classification method, component screening method, and component distribution ratio design method, which has a practical value.