In order to solve the problem of delay in construction of refabricated buildings caused by unreasonable quantification of uncertain factors in the classic critical chain buffer setting method,mainly considering three types of factors affecting the construction progress of prefabricated buildings,a buffer setting method based on complex entropy, multiresource entropy and project team entropy was proposed based on the theory of information entropy.Partial least squares structural equation modeling was mainly introduced to solve the problem that project team entropy was difficult to measure, and an entropy model for buffer setting and correcting was proposed.The feasibility of the buffer setting method proposed in this study was verified through the example simulation.The method can effectively shorten the completion period of the prefabricated building project.