In order to determine the reasonable interlayer setting position of joint between new and old pavement reinforced by RoadMesh steel wire mesh to resist the reverse bending failure effect of the top of asphalt pavement caused by differential settlement of widening subgrade,relying on the real old road widening project,three interlayer reinforcement schemes were selected such as between asphalt surface layers (scheme 1),between surface layer and base layer (scheme 2) and between base layers （scheme 3).The 10 mm maximum void value of differential settlement was set at the surface of new subgrade under the outer edge of new shoulder.Through the corresponding 3D finite element modeling and numerical simulation,the comparative analysis of mechanical response of widening asphalt pavement structure was carried out before and after the RoadMesh steel wire mesh reinforcement and for the different interlayer reinforcement schemes. The results show that the peak value of the maximum tensile stress of pavement surface near the joint and the pavement surface deflection value of double wheel clearance center can be used as the main control indexes of widening asphalt pavement structure for resisting differential settlement of widening subgrade.The order of simulation results for the two indexes under each scheme is scheme 1< scheme 2 < scheme 3 < unreinforced scheme,and the two indexes of scheme 1are 53.4% and 60.6% lower than those of the unreinforced scheme,respectively,which indicates that the joint between new and old pavement reinforced by the RoadMesh steel wire mesh can significantly improve the ability of widening asphalt pavement structure to resist differential settlement of widening subgrade.The closer the reinforced interlayer is to the pavement surface,the more significant the reinforcement effect for resisting reverse bending failure effect is.Therefore,the optimum reinforcement interlayer is between surface layers,and the suitable reinforcement interlayer is between surface layer and base layer.The results can provide reference for the reinforcement design of widening asphalt pavement.