In order to study the interaction effect between embedded strain sensor and asphalt mixture, the finite element model of beam specimen embedded with strain sensor under four-point bending loading condition was established by using ABAQUS finite element software. The effects of load size, sensor pullrod length and sensor encapsulating material modulus on mechanical response and stress concentration of asphalt concrete beam specimen and sensor were analyzed. The results show that after the sensor is embedded in the asphalt mixture beam specimen, the stress concentration phenomenon occurs in the beam specimen, which is located in the asphalt mixture contacting with the sensor flange. But the stress concentration coeficient is small, the maximum value is only 2.95. The sensor also has the stress concentration phenomenon in the pulrod, and the maximum value of the stress concentration coeficient is 26.83, which is much higher than that of the beam specimen.