In order to ensure the structural safety of the steel-concrete joint section during the hoisting process, the steel-concrete joint section of a cable-stayed bridge with 530 m main span was taken as the study object. Considering the nonlinearity of the materials, the steel fiber reinforced concrete(SFRC) elastoplastic damage constitutive relationship based on the test results was used for reference, and the hoisting of the poured steel-concrete joint section was simulated by the finite element software ABAQUS. The simulation results show that the lifting load during hoisting is unfavorable to the concrete inside the joint section. It is difficult to completely ensure the structural safety by simply installing the lifting lugs on the original structure based on similar construction experience. It is necessary to reinforce under the steel beam roof before hoisting. By locally reforcing the steel beams, the tensile stress of SFRC during hoisting is reduced from 4.2 MPa to 1.7 MPa, and the structural safety is ensured.