The aerodynamic characteristics of the wind-vehicle-bridge system are investigated using numerical simulation method in this paper. The aerodynamics characteristics of the vehicle and the bridge section at different cases are simulated and the aerodynamic influence between the vehicle and the bridge is analyzed. The results show that the aerodynamic coefficients of the vehicle and bridge for the coupled vehiele-brdige system are different from those of the vehicle and bridge for the single vehicle system and the single bridge system. So the aerodynamic influence between the vehicle and the bridge should be considered for the vibration analysis of the coupled wind-vehicle bridge system.